Methylation

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What is methylation?

Methylation is a process in the human body where methyl groups are added to DNA molecules. We all are made up of DNA molecules. Maybe you’ve heard of someone with impaired methylation. What does that mean exactly? An impaired Methylation means if you aren’t capable of adding methyl groups towards Transcription, which is the first step in gene expression. Your body is not able to function as well. Think of it like not having the instruction manual- like a Morse Code for your body to do what it needs to do; so you are basically missing patterns of the code because you can’t get the process of Methylation started.

Why should you care?

Your DNA strand is what is being copied in the process of transcription. If it can not copy, then the messenger RNA process never happens in your body. The final result is that no DNA copy is transcribed for the messenger RNA to make proteins in your body. The Morse Code is lost in transcription! If you have inflammation in your body, get the following blood tests performed:

C-reactive protein

ANA (autoimmune)

Ferritin (active iron)

If you have or suspect issues with your metabolism or your thyroid, it is recommended to get the following: Thyroid Stimulating Hormone (TSH), active T3 and active T4, free T3 and free T4, T3 uptake, Reverse T3, Thyroid Peroxidase (TPO), Thyroglobulin (TGB), cortisol (at least AM cortisol).

Reverse T3 is the T3 that never converts in the thyroid gland. It is more of a measurement of adrenal dysfunction than thyroid function. Thyroid peroxidase is an enzyme expressed by the thyroid and secreted into colloid. It specifically oxidizes iodide ions to form iodine atoms needed to produce thyroid hormones. Thyroglobulin is the precursor to the thyroid hormones, it’s one of the building blocks to make the thyroid hormones. It is entirely contained in the thyroid gland.

Other Tests Aside from the normal Bloodwork

Suspecting that you are suffering from high cholesterol? Or a liver dysfunction or known absorption issues with fats? We recommend a Comprehensive Liver panel; this would include apolipoprotein testing to look deeper into your “bad” cholesterol. After all cholesterol is not bad, it just depends on what flavor of cholesterol you have. Apolipid or Fraction testing is how you determine your flavor. If symptoms persists, it’s probably time to have yourself checked. Register to Longevity Lab Membership and schedule a consult with a Longevity Physician today. Already a member? Login to your account and schedule through your member’s dashboard.

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