Metabolism Test


Organic Acids are chemical compounds excreted in the urine of mammals that are products of metabolism. If you are feeling something is off, get blood work taken, and no clinical findings are present, an OAT test should be your next step. When you get your urine tested here in the OAT test, we are able to see functional changes in the metabolic chemistry that simply does not show up on a blood test. This gets to the root of the health problem!



The following areas are tested in the OAT test: Candida Overgrowth, Toxins related to Clostridia such as C. difficile; Oxalates; Mitochondrial Imbalances; Neurotransmitter Imbalances; Folate Metabolism; Key Nutritional Markers for Health; and Glutathione Deficiency.

Candida Overgrowth. The OAT is overall more sensitive for candida analysis because it is detecting chemical production within the digestive system that is reflective of these organism’s metabolic activity, and tissue invasion along the mucosal lining of the gut.

Clostridia. The OAT evaluates for specific toxins related to various clostridia bacteria. Clostridia bacteria such as Clostridia difficile (C. diff.) can lead to digestive problems and poor health.

Oxalates. Oxalate (oxalic acid) is a compound found in many foods such as nuts (e.g., almonds), fruit (e.g., berries) and certain vegetables (e.g., spinach). Oxalate can also be produced by candida overgrowth, aspergillus mold, as well as certain metabolic imbalances linked to deficiency in oxalate metabolizing enzymes. High oxalate is often associated with joint and muscle pain but can lead to bladder and bowel discomfort as well. Severe cases of oxalate accumulation can cause kidney stones. Oxalate can trap heavy metals such as mercury, lead, and arsenic in the body and lead to mineral imbalances.

Mitochondrial Imbalances. The mitochondria are the energy factories of our cells producing large amounts of adenosine triphosphate (ATP). ATP acts as energy currency for our body. Mitochondria are often stressed because of toxins from candida, bacteria, oxalate, heavy metals, and environmental chemicals. Mitochondrial dysfunction is common in many chronic health disorders. Neurotransmitter Imbalances. OAT evaluates for imbalances in dopamine and norepinephrine. The relationship between these two important brain chemicals is critical for attention, focusing, mood, calmness, and other functions of the nervous system. Additionally, deficiency of excess of serotonin, is also an important brain chemical for

mood, fine and gross motor skills, calmness, and sleep. Quinolinic acid (QA) evaluation identified on the OAT, indicates a toxic load in the brain triggering increase receptor activity that allows for increase influx of calcium into a brain cell. This mechanism can lead to a host of cell problems causing or contributing to brain cell death and destruction. For these reasons, it is beneficial to perform an OAT before implementing high dose amino acid L-tryptophan supplementation which is often used to assist with sleep or some mental health disorders.

Folate Metabolism. OAT evaluates for two specific chemicals related to folate metabolism. Folate is linked to the methylation cycle that supports the inner workings of the cells related to DNA function and metabolism. Poor folate metabolism can lead to cognitive problems.

Nutritional Markers. OAT evaluates for various nutritional markers such as vitamin B6, vitamin B5, vitamin C, CoQ10, as well as N-Acetylcysteine (NAC). NAC is necessary as a precursor for the antioxidant glutathione.

Glutathione Deficiency. Glutathione is a powerful antioxidant in our cells and protects against toxicity. The lack of glutathione leads to oxidative stress within the brain and nervous system which causes poor attention, focusing, and overall cognitive challenges. Glutathione deficiency can also compromise immune system health. Glutathione is a necessary compound involved liver detoxification of chemicals.


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